ZBTB7B Monoclonal Antibody - BT-MCA3140

ZBTB7B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3140-50, BT-MCA3140-100

Citations, Manuals and MSDS Available upon request.

Background: ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Research Areas: Epigenetics and nuclear signaling, Immunology

Target Protein: ZBTB7B

Applications: WB, IHC, ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7C12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ZBTB7B

Immunogen: Purified recombinant fragment of human ZBTB7B expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 58kDa

UniProt Accession: O15156

Synonyms: THPOK, ZFP67, ZBTB15, c-Krox, hcKrox, ZNF857B, DKFZp686G01254, ZBTB7B

GeneID: 51043

Research Use Only