ZNF384 Polyclonal Antibody - BT-AP09722

ZNF384 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09722-20, BT-AP09722-50, BT-AP09722-100

Citations, Manuals and MSDS Available upon request.

Background: ZNF384 encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: ZNF384

Applications: WB, ELISA

Reactivity: Human, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: ZNF384 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 63219

UniProt Accession: Human: Q8TF68; Rat: Q9EQJ4

Synonyms: ZNF384; CAGH1; CIZ; NMP4; TNRC1; Zinc finger protein 384; CAG repeat protein 1; CAS-interacting zinc finger protein; Nuclear matrix transcription factor 4; Nuclear matrix protein 4; Trinucleotide repe

GeneID: Human: 171017; Rat: 171018

Research Use Only