Product Description

ZNF486 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18362-60, E-AB-18362-120, E-AB-18362-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ZNF486

Target Synonym: KRAB box only protein 2 ; KRBO2 ; Zinc finger protein 486

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96H40

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF486 (Zinc finger protein 486), also known as KRAB domain only protein 2, is a 216 amino acid nuclear protein that contains one KRAB domain and two C2H2-type zinc fingers. The gene encoding ZNF486 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1, 400 genes and is recognized for having the greatest gene density of the human chromosomes. May be involved in transcriptional regulation.

Concentration: 0.9 mg/mL

Immunogen: Fusion protein of human ZNF486

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:250, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only