Product Description

ZYX Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11800-50, MB11800-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q15942

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Zyxin binds alpha-actinin and the CRP proteins and is implicated in the regulation and modulation of actin filaments organization, cell adhesion, cell motility, mitosis, and signal transduction. Zyxin may shuttle between focal adhesion plaques and the nucleus. It has been suggested that zyxin is involved in gene transcription by its association with transcription factors in the nucleus.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 61 kDa; Observed MW: 78 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of ZYX in Hela using ZYX antibody, and DAPI., Western blot analysis of ZYX in PC-3, HUVEC lysates using ZYX antibody., Western blot analysis of ZYX in C6, rat Brain lysates using ZYX antibody, Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Zyxin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: ESP2; HED2; ZYX; Zyxin2

Immunogen: A synthetic peptide of human Zyxin

Conjugate: Unconjugated

Modification: Unmodified