Product Description

β-Catenin Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: EM1183-50, EM1183-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.

Reactivity: Human, Rat, Mouse

Host: Mouse

Applications: WB, IHC

Alternate Names: b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286

Clonality: Monoclonal

Immunogen: Recombinant Protein

Isotype: IgG1

Dilution: WB 1:1,000-2,000   IHC 1:200-500

Concentration: 1mg/mL,

Observed Band (KD): 92kDa

Subcellular Location: Cell junction,  Cell membrane,  Cell projection,  Cytoplasm,  Cytoskeleton,  Membrane,  Nucleus,  Synapse

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Research Use Only