α-tubulin Monoclonal Antibody (8F11) - RA10546

α-tubulin Monoclonal Antibody (8F11)

Size: 50μL, 100μL

Catalogue Numbers: RA10546-50, RA10546-100

Citations, Manuals and MSDS Available upon request.

Background: tubulin alpha 1a (TUBA1A) Homo sapiens Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF/ICC; IP

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 7846/10376

Protein MW (KDa): 52

SWISS: Q71U36/P68363

Source: Mouse

Research Use Only