Product Description

μlK1 (phospho-Ser636) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: AP4007-50, AP4007-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: μlK1 andμlK2 (for UNC-51-like kinase) encode similar amino-terminal serine/threonine kinase domains, a proline/serine-rich (PS) domain, and a species conserved carboxyl-terminal domain. Both share homology with the UNC-51 kinase from Caenorhabditis elegans and the APG1 kinase in yeast, which are involved in axonal extension and growth, and autophagy, respectively.μlK1 andμlK2 are thought to auto-phosphorylate the PS domain in vitro, and the significant homology among vertebrates suggest thatμlK1 andμlK2 are involved in the regμlation of fundamental biological processes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Serine/threonine-protein kinaseμlK1, Autophagy-related protein 1 homolog, ATG1, Unc-51-like kinase 1,μlK1, KIAA0722

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from humanμlK1 around the phosphorylation site of Ser638.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: μlK1 (phospho-Ser638) polyclonal antibody detects endogenous levels ofμlK1 protein only when phosphorylated at Ser638.

Molecular Weight: ~ 150 kDa

Pathway: PI3K AKT signaling, Autophagy Signaling, MTOR signaling,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O75385

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only