14-3-3 ζ (phospho Ser58) Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA21458-50, RA21458-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ) Homo sapiens This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and Sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, IHC-p, IF/ICC, ELISA Alternate Names: YWHAZ, 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. Molecular Weight: 30 Protein Molecular Weight (kDa): 30 Storage: -20°C/1 year Human Gene ID: 7534 Human SwissProt Number: P63104 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only