14-3-3 Theta/Tau Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP00013-20, BT-AP00013-50, BT-AP00013-100
Citations, Manuals and MSDS Available upon request.
Background: Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Research Areas: Signal Transduction; Stem Cells
Target Protein: YWHAQ
Applications: WB, IHC-p, IF, ELISA
Reactivity: Human, Mouse, Rat
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: 14-3-3 theta/Tau Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 27764
UniProt Accession: Human: P27348; Mouse: P68254; Rat: P68255
Synonyms: YWHAQ; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
GeneID: Human: 10971; Mouse: 22630; Rat: 25577
Research Use Only