Product Description

A-Myb Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES6300-50, ES6300-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Strong transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: MYBL1, AMYB, Myb-related protein A, A-Myb, Myb-like protein 1

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human MYB-A. AA range:231-280

Isotype: IgG

Target: A-Myb

Specificity: A-Myb Polyclonal Antibody detects endogenous levels of A-Myb protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in a variety of lymphoid and solid tumor lines cultured in vitro,

Observed Band (KD): 85kD

Function: Function: Strong transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells
Similarity: Contains 3 HTH myb-type DNA-binding domains
Subunit: Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2
Tissue Specificity: Expressed in a variety of lymphoid and solid tumor lines cultured in vitro

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: MYBL1

Protein Name: Myb-related protein A

Mouse Gene ID: 17864

Mouse SwissProt Number: P51960

Research Use Only