ABflo® 450 Rabbit anti-Human EGFR Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A26808-100, A26808-200, A26808-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 44kDa/69kDa/77kDa/134kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 1956
SWISS: P00533
Alternate Names: ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC, 5 μl per 10^6 cells in 100 μl volume
Research Areas: Protein phosphorylation, Cancer, Tumor biomarkers, Signal Transduction, G protein signaling, Kinase, Tyrosine kinases, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, Jak-Stat-IL-6 Receptor Signaling Pathway, Cardiovascular, Angiogenesis
NCBI Alias: EGFR
Modifications: Unmodified
Conjugate: ABflo® 450. Ex:406nm. Em:445nm.
Clone Number Info: ARC61443
Research Use Only