ABflo® 488 Rabbit anti-Human CD105/Endoglin Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24318-100, A24318-200, A24318-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 67kDa/70kDa Immunogen: Recombinant protein (or fragment).
Species: human
GeneID: 2022
SWISS: P17813
Alternate Names: ENG; END; HHT1; ORW1; endoglin
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Tumor biomarkers, Immunology and Inflammation, CD markers, Stem Cells, Endothelial Progenitors, Mesenchymal Stem Cells, Cardiovascular, Cardiovascular Markers, Endothelial Cells
NCBI Alias: ENG
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC62399
Research Use Only