ABflo® 488 Rabbit anti-Human CD369/Dectin-1 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24271-100, A24271-200, A24271-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 5kDa/8kDa/13-27kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 64581
SWISS: Q9BXN2
Alternate Names: CLEC7A; BGR; CANDF4; CD369; CLECSF12; DECTIN1; SCARE2; C-type lectin domain containing 7A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology and Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway
NCBI Alias: CLEC7A
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC61646
Research Use Only