ABflo® 488 Rabbit anti-Mouse CD140b/PDGFR beta Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A26690-100, A26690-200, A26690-500
Citations, Manuals and MSDS Available upon request.
Background: Enables platelet-derived growth factor-activated receptor activity and signaling receptor binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; protein phosphorylation; and vasculature development. Acts upstream of or within several processes, including animal organ development; response to ceramide; and ruffle assembly. Located in cell surface; cytoplasm; and ruffle. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; nervous system; and sensory organ. Used to study basal ganglia calcification; infantile myofibromatosis; myeloproliferative neoplasm; and severe nonproliferative diabetic retinopathy. Human ortholog(s) of this gene implicated in basal ganglia calcification; glioblastoma; infantile myofibromatosis; myeloproliferative neoplasm (multiple); and renal cell carcinoma. Orthologous to human PDGFRB (platelet derived growth factor receptor beta).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 123kDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 18596
SWISS: P05622
Alternate Names: Pdgfr; CD140b; PDGFR-1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cardiovascular Angiogenesis Growth Factors OtherSignal Transduction Protein Phosphorylation Tyrosine Kinases Receptor Tyrosine KinasesSignal Transduction Growth Factors/Hormones PDGFMicrobiology Organism Virus RNA Virus ssRNA positive strand virus SARS CoronavirusCancer Growth factors PDGFCancer Oncoproteins/suppressors Oncoproteins Growth factor receptorsCardiovascular Atherosclerosis Vascular Inflammation Inflammatory mediatorsNeuroscience Development
NCBI Alias: Pdgfrb
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC69297
Research Use Only