ABflo® 500 Rabbit anti-Human/Monkey CD8a Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A26731-100, A26731-200, A26731-500
Citations, Manuals and MSDS Available upon request.
Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human, Cynomolgus
Protein Weight: 21kDa/25kDa/30kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 925
SWISS: P01732
Alternate Names: CD8; p32; Leu2; CD8alpha
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology and Inflammation, CD markers, Stem Cells
NCBI Alias: CD8A
Modifications: Unmodified
Conjugate: ABflo® 500. Ex:410nm. Em:501nm.
Clone Number Info: ARC55248
Research Use Only