ABflo® 594 Rabbit anti-Human CD170/Siglec-5 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A23700-100, A23700-200, A23700-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 61kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 8778
SWISS: O15389
Alternate Names: CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology Inflammation, CDs
NCBI Alias: SIGLEC5
Modifications: Unmodified
Conjugate: ABflo® 594. Ex:588nm. Em:604nm.
Clone Number Info: ARC60966
Research Use Only