ABflo® 594 Rabbit anti-Human/Mouse CD276/B7-H3 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24590-100, A24590-200, A24590-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human, Mouse
Protein Weight: 33kDa/52kDa/57kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 80381
SWISS: Q5ZPR3-2
Alternate Names: CD276; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2; CD276 antigen
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Tumor biomarkers, Immunology and Inflammation, CD markers, Stem Cells, Hematopoietic Progenitors
NCBI Alias: CD276
Modifications: Unmodified
Conjugate: ABflo® 594. Ex:588nm. Em:604nm.
Clone Number Info: ARC54779
Research Use Only