ABflo® 610 Rat anti-Mouse MHC Class II (I-A/I-E) Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27307-100, A27307-200, A27307-500
Citations, Manuals and MSDS Available upon request.
Background: Predicted to enable several functions, including MHC class II receptor activity; peptide antigen binding activity; and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II. Predicted to be located in external side of plasma membrane and immunological synapse. Predicted to be part of MHC class II protein complex. Predicted to be active in late endosome membrane and lysosomal membrane. Is expressed in lung. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); bacterial infectious disease (multiple); eye disease (multiple); and sarcoidosis (multiple). Orthologous to several human genes including HLA-DRB5 (major histocompatibility complex, class II, DR beta 5).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 30kDa/32kDa/26kDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 14969/14961/381091/14960
SWISS: P18468/P06342/Q3U060/P14435
Alternate Names: Eb; Ia4; H2Eb; Ia-4; H-2Eb;IAb; Ia2; Ia-2; Abeta; H-2Ab; H2-Ab; Rmcs1; I-Abeta; Ia5; Ia-5; H-2Eb2; Iebeta2; A130038H09Rik; Ia1; H2Aa; Ia-1; H-2Aa; Aalpha; IAalpha; I-Aalpha
Source: Rat
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology, Adaptive Immunity, MHC Class II
NCBI Alias: MHC Class II (I-A/I-E)
Modifications: Unmodified
Conjugate: ABflo® 610. Ex:421nm. Em:612nm.
Clone Number Info: ATC50002
Research Use Only