ABflo® 647 Rabbit anti-Human IL-10RA/CD210 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A28197-100, A28197-200, A28197-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 63 kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 3587
SWISS: Q13651
Alternate Names: CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology Inflammation, CDs, Cytokines, Interleukins, Cell Intrinsic Innate Immunity Signaling Pathway
NCBI Alias: IL10RA
Modifications: Unmodified
Conjugate: ABflo® 647. Ex:648nm. Em:664nm.
Clone Number Info: ARC63596
Research Use Only