ABflo® 647 Rabbit anti-Human TrkA Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A23974-100, A23974-200, A23974-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 77kDa/83kDa/86kDa/87kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 4914
SWISS: P04629
Alternate Names: NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; neurotrophic receptor tyrosine kinase 1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology and Developmental Biology, Growth factor, Neuroscience
NCBI Alias: NTRK1
Modifications: Unmodified
Conjugate: ABflo® 647. Ex:648nm. Em:664nm.
Clone Number Info: ARC61412
Research Use Only