ACAC1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A25224-20, A25224-100
Citations, Manuals and SDS Available upon request.
Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Synonyms: ACC; ACAC; ACC1; ACCA; Acac1; hACC1; ACACAD; ACCalpha; ACACalpha; acetyl-ACC1
GeneID: 31
Swiss Prot: Q13085
Tested Applications: ELISA, IHC-P
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 266kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant Protein corresponding to a sequence within amino acids 1-75 of human ACAC1 (NP_942133.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Recommended Dilutions: IHC-P: 1:50 - 1:200
Research Areas: Protein phosphorylation, Endocrine Metabolism, Lipid Metabolism, AMPK Signaling Pathway, Warburg Effect
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm
Keywords: 31, sc-26817, sc-30212, ACAC, ACACA, ACC, ACC1, ACCA, Acetyl CoA carboxylase 1, ACACAD, acetyl-CoA carboxylase alpha, acetyl-CoA carboxylase 1, ACC-alpha, acetyl-Coenzyme A carboxylase alpha, Q13085, Acetyl-CoA Carboxylase Alpha, Acetyl-Coenzyme A Carboxylase Alpha, Acetyl-CoA Carboxylase 1, ACC-Alpha, EC 6.4.1.2, sc26817, sc 26817, sc30212, sc 30212, acetyl-ACC1
Symbol: ACACA
Category: Polyclonal Antibodies
Research Use Only