Acetyl-Histone H4-K91 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A7409-20, A7409-100
Citations, Manuals and SDS Available upon request.
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Synonyms: H4; H4/n; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4F2; H4FN; FO108; H4-16; H4C11; H4C12; H4C13; H4C15; H4C16; HIST2H4; HIST2H4A; Acetyl-Histone H4-K91
GeneID: 8359
Swiss-Prot: P62805
Reactivity: Human, Mouse, Rat, Other (Wide Range Predicted)
Calculated Molecular Weight: 11kDa
Observed Molecular Weight: 17kDa
Immunogen: A synthetic acetylated peptide around K91 of human Histone H4 (NP_003529.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IF/ICC: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling
Modifications: Acetyl K91
Conjugate: Unconjugated
Positive Samples: NIH/3T3
Cellular Location: Chromosome, Nucleus
Category: Acetylated Antibodies
Citations, Manuals and SDS Available upon request.