Actin-α cardiac muscle rabbit pAb - ES3840

Actin-α cardiac muscle rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3840-50, ES3840-100

Citations, Manuals and MSDS Available upon request.

Background: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008],

Alternate Name: ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from Actin-α cardiac muscle . at AA range: 1-80

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 42kD

Human Gene ID: 70

Human SWISS Prot NO: P68032

Subcellular Location: Cytoplasm, cytoskeleton.

Research Use Only