Product Description

ACTY Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18465-50, ES18465-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human ACTY AA range: 29-79

Isotype: IgG

Target: ACTY

Specificity: This antibody detects endogenous levels of ACTY at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 41kD

Fields: Amyotrophic lateral sclerosis, Huntington disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection

Function: Function: Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome
Similarity: Belongs to the actin family
Similarity: Belongs to the actin family. ARP1 subfamily

Subcellular Location: Cytoplasm, cytoskeleton Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Storage and Stability: -20°C/1 year

Gene Name: ACTR1B CTRN2

Protein Name: ACTY

Mouse Gene ID: 226977

Mouse SwissProt Number: Q8R5C5

Research Use Only