ACVR1C Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0678-20, A0678-100
Citations, Manuals and MSDS Available upon request.
Background: ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 55kDa
Observed Molecular Weight: 55kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 130399
SWISS: Q8NER5
Alternate Names: ALK7; ACVRLK7; ACVR1C
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:100 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Kinase, Apoptosis, Growth factors.
NCBI Alias: ACVR1C
Research Use Only