Adducin γ (P452) Polyclonal Antibody
Catalogue Numbers: BS2209-50, BS2209-100
Sizes: 50µl, 100µl
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9UEY8
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB IHC IF
All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200
Background: Adducins are a family of cytoskeleton proteins encoded by three genes (α, β and γ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and adducins are central in the cortical actin network organization. Adducin α is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin α and Adducin γ is ubiquitous in contrast to the restricted expression of Adducin β. Adducin β is expressed at high levels in brain andhematopoietic tissues, such as bone marrow in humans, and spleen in mice.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Adducin γ (P452) polyclonal antibody detects endogenous levels of Adducin γ protein.
Extra Notes: Western blot (WB) analysis of Adducin γ (P452) polyclonal antibody at 1:500 dilution
Lane1:BV2 whole cell lysate(40ug)
Lane2:PC12 whole cell lysate(40ug)
Lane3:LO2 whole cell lysate(40ug)
Lane4:A549 whole cell lysate(40ug)
Lane5:HepG2 whole cell lysate(40ug)
Bioworld Molecular Weight: ~ 82 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: ADD3; ADDG; ADDL; Adducin 3 (gamma); Adducin 3; Adducin-like protein 70; Gamma-adducin; Adducinγ
Immunogen: Synthetic peptide, corresponding to amino acids 420-471 of Human Adducin γ.
Conjugate: Unconjugated
Modification: Unmodified