Product Description

AF1L1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18445-50, ES18445-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Actin filament-associated protein 1-like 1 (AFAP1-like protein 1)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human AF1L1 AA range: 180-230

Isotype: IgG

Target: AF1L1

Specificity: This antibody detects endogenous levels of AF1L1 at Human/Mouse/Rat

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.325% sodium azide.

Expression: Expressed in breast, colon and brain, In all 3 tissues, expressed in the microvasculature (at protein level), In addition, in the breast, found in the contractile myoepithelial cell layer which surrounds the breast ducts (at protein level), In the colon, expressed in the mucous membrane and colonic crypts and in the smooth muscle cell layer which provide movement of the colon (at protein level), In the cerebellum, localized around the Purkinje neurons and the granule cells of the granular layer, but not inside cell bodies (at protein level), Outside of the cerebellar cortex, expressed in glial cells (at protein level), Highly expressed away from the cell bodies within the dentate nucleus (at protein level),

Observed Band (KD): 85kD

Function: PTM: Phosphorylated upon DNA damage, probably by ATM or ATR
Similarity: Contains 2 PH domains

Subcellular Location: Cytoplasm Cell projection, podosome Cell projection, invadopodium Cytoplasm, cytoskeleton, stress fiber

Storage and Stability: -20°C/1 year

Gene Name: AFAP1L1

Protein Name: AF1L1

Mouse Gene ID: 106877

Mouse SwissProt Number: Q8BZI0

Rat Gene ID: 291565

Rat SwissProt Number: D4AB98

Research Use Only