ALDH5A1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16074-20, A16074-100
Citations, Manuals and MSDS Available upon request.
Background: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD (+) -dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 57kDa
Observed Molecular Weight: 57kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 7915
SWISS: P51649
Alternate Names: SSDH; SSADH; ALDH5A1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Amino acid metabolism, Lipid Metabolism, Neuroscience.
NCBI Alias: ALDH5A1
Research Use Only