AMPKα1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA21851-50, RA21851-100 Citations, Manuals and MSDS Available upon request. Background: protein kinase AMP-activated catalytic subunit alpha 1 (PRKAA1) Homo sapiens The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008], Condition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. Storage Instructions: -20°C/1 year Recommended dilutions: WB: 1:500-1000 IHC: 1:200-500 Alternative Names: PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; YM3432 Applications: WB; IHC-p; IF (paraffin section) Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 5562 Protein MW (KDa): 63 SWISS: Q13131 Source: Rabbit Research Use Only