AMPK α1 Monoclonal Antibody (5G11) Sizes: 50μL, 100μL Catalogue Numbers: RA10759-50, RA10759-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: protein kinase AMP-activated catalytic subunit alpha 1 (PRKAA1) Homo sapiens The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008], Reactivity: Human, Rat, Mouse Host: Mouse Applications: WB, IHC-p, IF(paraffin section) Alternate Names: PRKAA1, AMPK1, 5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1 Clonality: Monoclonal Dilution: WB 1:1000-2000, IHC 1:50-100 Storage: -20°C/1 year Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Human Gene ID: 5562 Protein Molecular Weight（KDa): 63 Molecular Weight: 63 Research Use Only