Product Description

ANFC Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES11810-50, ES11810-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: ANFC

Specificity: ANFC Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: [CNP-22]: In the kidney, predominantly expressed in the distal tubular cells (at protein level),

Observed Band (KD): 13kD

Fields: cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Fluid shear stress and atherosclerosis

Function: Function: Vasorelaxant activity. Has a cGMP-stimulating activity
Similarity: Belongs to the natriuretic peptide family

Subcellular Location: Secreted

Storage and Stability: -20°C/1 year

Gene Name: NPPC CNP2

Protein Name: C-type natriuretic peptide [Cleaved into: CNP-22, CNP-29, CNP-53]

Mouse SwissProt Number: Q61839

Rat SwissProt Number: P55207

Research Use Only