Anti-SARS-CoV Spike S1 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-V1350-50, E-AB-V1350-100
Citations, Manuals and MSDS Available upon request.
Target Synonym: coronavirus s1; coronavirus spike; cov spike; ncov RBD; ncov s1; ncov spike; novel coronavirus RBD; novel coronavirus s1; ; novel coronavirus spike; RBD; S1; Spike RBD
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: SARS
Application: WB, ELISA
Isotype: IgG2a
Clonality: Monoclonal
Clone No.: 8
Background: The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.
Concentration: 1mg/mL
Immunogen: Recombinant SARS-CoV S1 Protein (His Tag)（Active）
Buffer: 0.2 μm filtered solution in PBS
Purification Method: Protein A Affinity
Dilution: WB 1:1000-1:5000 ELISA 1:1000-1:2000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only