Product Description

AP3M2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18306-50, ES18306-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 3 (AP-3), which belongs to the adaptor complexes medium subunits family. The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human AP3M2 AA range: 274-324

Isotype: IgG

Target: AP3M2

Specificity: This antibody detects endogenous levels of AP3M2 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 46kD

Fields: Lysosome

Function: Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes
Similarity: Belongs to the adaptor complexes medium subunit family
Similarity: Contains 1 MHD (mu homology) domain
Subunit: Adaptor protein complex 3 (AP-3) is an heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2)

Subcellular Location: Golgi apparatus Cytoplasmic vesicle membrane, Peripheral membrane protein, Cytoplasmic side Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex

Storage and Stability: -20°C/1 year

Gene Name: AP3M2

Protein Name: AP3M2

Mouse Gene ID: 64933

Mouse SwissProt Number: Q8R2R9

Rat Gene ID: 140667

Rat SwissProt Number: P53678

Research Use Only