APBA1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18582-20, A18582-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP) . It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Category: Polyclonal Antibodies
Applications: IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 93kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 320
SWISS: Q02410
Alternate Names: X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA; APBA1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Neurodegenerative Diseases Markers.
NCBI Alias: APBA1
Research Use Only