Product Description

APC1  (phospho-S688) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS4375-50, BS4375-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: APC1 is 1 of at least 11 subunits of the anaphase promoting complex (APC), which functions at the metaphase to anaphase transition of the cell cycle and is regμlated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regμlatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Anaphase-promoting complex subunit 1, APC1, Cyclosome subunit 1, Mitotic checkpoint regμlator, Testis-specific gene 24 protein, ANAPC1, TSG24

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: Synthetic phosphopeptide derived from human APC1 around the phosphorylation site of Serine 688

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: p-APC1 (S688) pAb detects endogenous levels of APC1 protein only when phosphorylated at Ser688.

Molecular Weight: ~ 216 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9H1A4

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only