AREG Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12680-20, A12680-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
Category: Polyclonal Antibodies
Applications: IF/ICC, ELISA
Cross-reactivity: Mouse
Protein Weight: 28kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 374
SWISS: P15514
Alternate Names: AR; SDGF; AREGB; CRDGF; AREG
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, Cytokines.
NCBI Alias: AREG
Research Use Only