Arrestin-β-1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22094-50, RA22094-100
Citations, Manuals and MSDS Available upon request.
Background: arrestin beta 1 (ARRB1) Homo sapiens Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: ARRB1; ARR1; Beta-arrestin-1; Arrestin beta-1
Applications: WB; IHC-p; IF/ICC; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 408
Protein MW (KDa): 50
SWISS: P49407
Source: Rabbit
Research Use Only