Product Description

ASB1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18239-50, ES18239-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene contains an ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, targeting them for ubiquitination and degradation. [provided by RefSeq, Aug 2016],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human ASB1 AA range: 76-126

Isotype: IgG

Target: ASB1

Specificity: This antibody detects endogenous levels of ASB1 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 37kD

Function: Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes
Function: May play a role in testis development (By similarity). Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins
Pathway: Protein modification, protein ubiquitination
Similarity: Contains 1 SOCS box domain
Similarity: Contains 6 ANK repeats
Subunit: Interacts with CUL5 and RNF7

Subcellular Location: intracellular,

Storage and Stability: -20°C/1 year

Gene Name: ASB1 KIAA1146

Protein Name: ASB1

Mouse Gene ID: 65247

Mouse SwissProt Number: Q9WV74

Research Use Only