Product Description

ASIC5 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18232-50, ES18232-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human ASIC5 AA range: 412-462

Isotype: IgG

Target: ASIC5

Specificity: This antibody detects endogenous levels of ASIC5 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Detected in small intestine, duodenum and jejunum, Detected at very low levels in testis and rectum,

Molecular Weight (Da): 56kD

Fields: Inflammatory mediator regulation of TRP channels

Function: Function: Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride
Similarity: Belongs to the amiloride-sensitive sodium channel family
Subunit: Homotetramer or heterotetramer
Tissue Specificity: Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum

Subcellular Location: Cell membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: ASIC5 ACCN5 HINAC

Protein Name: ASIC5

Mouse Gene ID: 58170

Mouse SwissProt Number: Q9R0Y1

Rat Gene ID: 63866

Rat SwissProt Number: Q9R0W5

Research Use Only