Product Description

ATAD5 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18217-50, ES18217-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human ATAD5 AA range: 1054-1104

Isotype: IgG

Target: ATAD5

Specificity: This antibody detects endogenous levels of ATAD5 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 203kD

Function: Function: Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. ATR may stimulate the RAD9A dissociation
Sequence Caution: Contaminating sequence. Potential poly-A sequence
Similarity: Belongs to the AAA ATPase family
Subunit: Interacts with RB1 predominantly in G1 phase via its LXCXE motif. Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: ATAD5 C17orf41 FRAG1

Protein Name: ATAD5

Mouse Gene ID: 237877

Mouse SwissProt Number: Q4QY64

Research Use Only