Product Description

ATD3A Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18214-50, ES18214-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human ATD3A AA range: 433-483

Isotype: IgG

Target: ATD3A

Specificity: This antibody detects endogenous levels of ATD3A at Human

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Overexpressed in lung adenocarcinomas (at protein level),

Molecular Weight (Da): 70kD

Function: Similarity: Belongs to the AAA ATPase family

Subcellular Location: Mitochondrion inner membrane, Single-pass membrane protein Mitochondrion matrix, mitochondrion nucleoid In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane (PubMed:20349121, PubMed:20154147) The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (PubMed:18063578)

Storage and Stability: -20°C/1 year

Gene Name: ATAD3A

Protein Name: ATD3A

Research Use Only