Product Description

ATG4a Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: EA347-50, EA347-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems, Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE), which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described, including three Atg8 proteins (GATE-16, GABARAP, and LC3) and four Atg4 homologs (Atg4A/autophagin-2, Atg4B/autophagin-1, Atg4C/autophagin-3, and Atg4D/autophagin-4).

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Apg4a, Atg4al, Autl2,Cysteine protease ATG4A antibody

Clonality: Polyclonal

Immunogen: Recombinant Protein

Isotype: IgG

Dilution: IHC 1:100-200

Concentration: 1mg/mL,

Observed Band (KD): 45kDa

Subcellular Location: Cytoplasm

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Research Use Only