Product Description

ATL4 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18199-50, ES18199-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human ATL4 AA range: 78-128

Isotype: IgG

Target: ATL4

Specificity: This antibody detects endogenous levels of ATL4 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in colon, heart, leukocyte, liver, lung, skeletal muscle, spleen, testis and placenta, Weaker expression in bone marrow, brain tissue, kidney and pancreas, Expression studies in fetal tissues reveal strong expression in heart, kidney, liver, lung and skeletal muscle, but weaker expression in fetal brain and skin,

Molecular Weight (Da): 118kD

Function: Caution: Although similar to members of the ADAMTS family, it lacks the metalloprotease and disintegrin-like domains which are typical of that family
Function: Positive regulation of apoptosis
Similarity: Contains 1 PLAC domain
Similarity: Contains 6 TSP type-1 domains
Subunit: Interacts with CTSB

Subcellular Location: Secreted, extracellular space, extracellular matrix Colocalizes with FMN1 microfibrils in the eye ECM

Storage and Stability: -20°C/1 year

Gene Name: ADAMTSL4 TSRC1 PP1396 UNQ2803/PRO34012

Protein Name: ATL4

Mouse Gene ID: 229595

Mouse SwissProt Number: Q80T21

Rat Gene ID: 310670

Rat SwissProt Number: Q4FZU4

Research Use Only