Product Description

BAG3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-40660-50, E-AB-40660-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: BAG3

Target Synonym: BAG family molecular chaperone regulator 3 ; BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BIS

Research Areas: Cancer,Cell Biology,Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O95817

Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

Concentration: 0.4mg/mL

Immunogen: Recombinant Human BAG3 protein expressed by E.coli

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Purification Method: Antigen Affinity Purification

Dilution: WB:1:500-1:1000

Calculated MW: 62 kDa

Observed MW: 80 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only