Product Description

BAIP3 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18100-50, ES18100-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This p53-target gene encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the secretin receptor family. It interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. This protein also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human BAIP3 AA range: 248-298

Isotype: IgG

Target: BAIP3

Specificity: This antibody detects endogenous levels of BAIP3 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Predominantly expressed in brain (PubMed:9790924), Also expressed in nonneural tissues such as breast and testes epithelium (PubMed:12498718),

Molecular Weight (Da): 131kD

Fields: Transcriptional misregulation in cancer

Function: Similarity: Contains 1 MHD1 (MUNC13 homology domain 1) domain
Similarity: Contains 1 MHD2 (MUNC13 homology domain 2) domain
Similarity: Contains 2 C2 domains
Subunit: Interacts with BAI1
Tissue Specificity: Predominantly expressed in brain

Subcellular Location: Cytoplasm, cytosol Recycling endosome membrane, Peripheral membrane protein Late endosome membrane, Peripheral membrane protein Golgi apparatus, trans-Golgi network membrane, Peripheral membrane protein Cell membrane, Peripheral membrane protein Rapidly recruited to the plasma membrane and to Golgi structures in response to increased intracellular calcium concentration

Storage and Stability: -20°C/1 year

Gene Name: BAIAP3 KIAA0734

Protein Name: BAIP3

Mouse SwissProt Number: Q80TT2

Research Use Only