Product Description

BCA3 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES1754-50, ES1754-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: AKIP1, BCA3, C11orf17, A-kinase-interacting protein 1, Breast cancer-associated gene 3 protein, PKA-interacting protein, Proline-rich protein BCA3

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human BCA3. AA range:111-160

Isotype: IgG

Target: BCA3

Specificity: BCA3 Polyclonal Antibody detects endogenous levels of BCA3 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle, Up-regulated in some breast cancer cell lines, Isoform 1 and isoform 3 are expressed in fetal brain,

Observed Band (KD): 26kD

Function: Subcellular Location: Locates to punctate spots
Subunit: Interacts with PRKACA
Tissue Specificity: Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain

Subcellular Location: Nucleus Locates to punctate spots

Storage and Stability: -20°C/1 year

Gene Name: AKIP1

Protein Name: A-kinase-interacting protein 1

Mouse SwissProt Number: Q9JJR5

Research Use Only