Product Description

Beta5-tubμlin Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66826-50, MB66826-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Tubμlin is a major cytoskeleton component that has five distinct forms, designated a, β, g, d and e Tubμlin. a and β Tubμlins form heterodimers which mμltimerize to form a microtubμle filament. Mμltiple β Tubμlin isoforms (β1, β2, β3, β4, β5, β6 and β8) have been characterized and are expressed in mammalian tissues. β1 and β4 are present throughout the cytosol, β2 is present in the nuclei and nucleoplasm, and β3 is a neuron-specific cytoskeletal protein. g Tubμlin forms the gammasome, which is required for nucleating microtubμle filaments at the centrosome. Both d Tubμlin and e Tubμlin are associated with the centrosome. d Tubμlin is a homolog of the Chlamydomonas d Tubμlin Uni3 and is found in association with the centrioles, whereas e Tubμlin localizes to the pericentriolar material. e Tubμlin exhibits a cellcycle-specific pattern of localization, first associating with only the older of the centrosomes in a newly duplicated pair and later associating with both centrosomes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: WB, IHC, IF/ICC

Alternate Names: TUBB5, Tubμlin beta chain, Tubμlin beta-5 chain

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human Beta5-tubμlin. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/10 - 1/50)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of Beta5-tubμlin protein.

Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P07437

Product: Mouse IgG2b. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only