Product Description

BEX2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES18062-50, ES18062-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human BEX2 AA range: 28-78

Isotype: IgG

Target: BEX2

Specificity: This antibody detects endogenous levels of BEX2 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe, Widely expressed in breast cancer cell lines,

Molecular Weight (Da): 14kD

Function: Caution: Was named BEX1 by some authors
Similarity: Belongs to the BEX family
Subunit: Interacts with OMP (By similarity). Interacts with LMO2, possibly leading to regulate the transcriptional activity of a DNA-binding complex containing LMO2
Tissue Specificity: Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe

Subcellular Location: Cytoplasm Nucleus

Storage and Stability: -20°C/1 year

Gene Name: BEX2

Protein Name: BEX2

Mouse Gene ID: 12069

Mouse SwissProt Number: Q9WTZ8

Rat Gene ID: 363498

Rat SwissProt Number: Q3MKQ1

Research Use Only