BMP2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A0231-20, A0231-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Synonyms: BDA2; BMP2A; SSFSC; SSFSC1; BMP2
GeneID: 650
Swiss Prot: P12643
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 45kDa
Observed Molecular Weight: 30kDa/38kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Extracellular Matrix, Bone, Growth factors, TGF-b-Smad Signaling Pathway, Wnt ��-Catenin Signaling Pathway, ESC Pluripotency and Differentiation, Immunology Inflammation, Cytokines, NF-kB Signaling Pathway, Stem Cells, Neural Stem Cells, Cardiovascular, Angiogenesis
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Hep G2
Cellular Location: Secreted
Keywords: 650, sc-6895, sc-6267, sc-9003, BMP 2, BMP 2A, BMP2, BMP2A, bone morphogenetic protein 2, Bone morphogenetic protein 2A, BDA2, bone morphogenetic protein 2A, P12643, Bone Morphogenetic Protein 2, Bone Morphogenetic Protein 2A, BMP-2A, SSFSC, BMP-2, bmp2, sc6895, sc 6895, sc6267, sc 6267, sc9003, sc 9003
Symbol: BMP2
Category: Polyclonal Antibodies
Research Use Only