Product Description

BRD1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17956-50, ES17956-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human BRD1 AA range: 399-449

Isotype: IgG

Target: BRD1

Specificity: This antibody detects endogenous levels of BRD1 at Human

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Highly expressed in testis,

Molecular Weight (Da): 116kD

Function: Function: Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity
Similarity: Contains 1 bromo domain
Similarity: Contains 1 PHD-type zinc finger
Similarity: Contains 1 PWWP domain
Subunit: Component of the MOZ/MORF composed at least of ING5, MYST3/MOZ, MYST4/MORF and one of BRPF1, BRD1/BRPF2 and BRPF3
Tissue Specificity: Highly expressed in testis

Subcellular Location: Nucleus Chromosome Localizes to transcription start sites

Storage and Stability: -20°C/1 year

Gene Name: BRD1 BRL BRPF2

Protein Name: BRD1

Research Use Only